Endocrine Abstracts

Introduction: Being overweight or obese are common characteristic of women affected by polycystic ovary syndrome (PCOS). Indeed, 50–70% of the women are obese and more likely to present with higher growth rate and obesity already from early childhood compared with women without the syndrome. Obesity predisposes women with PCOS to adverse metabolic outcomes such as metabolic syndrome, insulin resistance and diabetes. Recent studies have also revealed a high prevalence of e...

Background: The age at adiposity rebound (AR), at which BMI begins to rise after infancy around the age of 5 years, is associated with obesity and metabolic alteration in later life. Given that polycystic ovary syndrome (PCOS) has strong metabolic components, early growth patterns could reveal predisposition for PCOS. Thus, we aimed to investigate the associations of growth trajectories from birth to puberty with PCOS diagnosis,vbody composition and hyperandrogenism later in a...